Physical Activity, Sustained Sedentary Behavior, and Pain Modulation in Women with Fibromyalgia

Fibromyalgia (FM) has been conceptualized as a disorder of the central nervous system, characterized by augmented sensory processing and an inability to effectively modulate pain.

We previously reported that physical activity is related to brain processing of pain, providing evidence for a potential mechanism of pain management.

The purpose of this study was to extend our work by manipulating pain modulation and determining relationships to both physical activity and sustained sedentary behavior.

Eleven women with FM completed accelerometer measures of physical activity and underwent functional magnetic resonance imaging of painful heat, administered alone and during distracting cognitive tasks.

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