Phase I human trial gives high tolerability/safety grades to potent new XMRV/HIV antiretroviral

Previous in vitro trials found the new chemical entity CMX157 exhibits potent activity against XMRV (20x more than AZT & 800x more than tenofovir) and highly resistant HIV. CMX157 is a modification of tenofovir, an antiretroviral approved for treating HIV & chronic hepatitis B.

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